Preexisting TCR Clones in HNSCC Patients Treated with Dual Immune Checkpoint Inhibitors

Supplementary Table S9 from Huaibin Ge's research on head and neck squamous cell carcinoma (HNSCC). The dataset likely contains differentially expressed genes (DEGs) for pre-existing T-cell receptor (TCR) clones in patients before and after dual immune checkpoint inhibitor treatment. The data is published on figshare under a CC-BY-4.0 license and was last updated on June 1, 2026.

Use Cases

• Identify gene expression changes associated with pre-existing TCR clones based on the description of DEGs.
• Analyze molecular pathways involved in pathologic responses to dual checkpoint inhibitors based on the dataset's focus.
• Correlate pre-treatment TCR clonality with post-treatment transcriptional changes based on the pre/post treatment comparison implied in the title.

Strengths

• Dataset is small (3.4 KB), facilitating quick download and initial inspection.
• Data is openly licensed (CC-BY-4.0) for reuse and redistribution.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, authored by Huaibin Ge.

Collection Method

Likely derived from clinical research on HNSCC patients treated with dual immune checkpoint inhibitors.

Freshness

Last updated 2026-06-01 07:24:45; freshness should be verified.