Dairy Cow Diet Composition and Plasma-Milk Metabolomics Datasets

Yan Huang's supplementary tables provide diet composition and untargeted metabolomics data from a dairy cow study. The dataset includes seven Excel tables detailing total mixed ration composition and metabolite features for plasma and milk samples across different parity and metabolic status groups (CON, SCK, HK). It supports analysis of differential metabolites and parity-metabolic status interactions.

Use Cases

• Analyze differential metabolite results in plasma and milk across CON, SCK, and HK metabolic groups to identify metabolic disorder biomarkers.
• Investigate parity × metabolic status interaction results for milk metabolites to understand how cow parity influences metabolic responses.
• Use untargeted metabolomics features with retention time and m/z values from plasma samples for metabolite annotation and pathway analysis.
• Correlate total mixed ration composition data with differential metabolite analysis results to study diet-metabolome relationships.

Strengths

• Includes data from two distinct biological matrices: plasma and milk samples.
• Covers three defined metabolic status groups: CON (control), SCK, and HK (hyperketonemia).
• Provides results for both differential analysis and parity-metabolic status interaction analysis.
• Released under a permissive CC BY 4.0 license.

Limitations

• Sample size and number of rows are unknown, limiting assessment of statistical power.
• Data is contained within seven separate tables, requiring integration for holistic analysis.
• Metabolomics features are untargeted, requiring further validation for confident metabolite identification.

Provenance

Source

figshare, authored by Yan Huang.

Collection Method

Experimental data from a dairy cow study, likely involving LC-MS or GC-MS untargeted metabolomics.

Time Range

Experimental period unspecified.

Freshness

Last updated March 2026.

Geography

null