Health Economic Analysis of Outpatient vs Inpatient Antibiotic Therapy

This dataset contains an R analysis script and six publication-quality figures for a cost-consequence analysis comparing daptomycin-based outpatient parenteral antimicrobial therapy (OPAT) via elastomeric pump with standard inpatient treatment for serious gram-positive infections. The analysis, conducted from the perspective of the Croatian national health insurer (HZZO), includes deterministic sensitivity analysis, probabilistic Monte Carlo simulation, cost-effectiveness acceptability curves, budget impact analysis, and scenario analysis. The R script is fully annotated and compliant with CHEERS 2022 reporting guidelines.

Use Cases

• Replicating a health economic model based on the provided R script and annotated code
• Reviewing sensitivity analysis methods using the included tornado diagram figures
• Assessing budget impact and cost-effectiveness acceptability from the generated scenario analysis plots
• Adapting a CHEERS-compliant analysis framework for other therapeutic areas

Strengths

• Includes a fully annotated R script compliant with CHEERS 2022 reporting standards
• Contains six publication-quality figures (TIFF format) generated with ggplot2
• Analysis is based on a specific national health insurer perspective (Croatian HZZO)

Limitations

• No raw input data or column descriptions are provided, only analysis code and output figures
• The dataset size (1.7 MB) suggests it contains code and images, not a primary data table
• The 'Last updated' date of 2026-03-19 appears to be a future date, indicating a potential metadata error

Provenance

Source

Robert Likic

Collection Method

Created as supporting material for a published cost-consequence analysis.

Time Range

Analysis timeframe not specified.

Freshness

2026-03-19 18:24:25

Geography

Croatia (perspective of the HZZO national health insurer)