Molecular and Morphological Data on Activin A in DPSC-Mediated Vascular Stabilization

Experimental data supporting a study on the role of Activin A in vascular stabilization and dental pulp regeneration. The dataset includes results from ELISA, protein expression profiles, HUVEC monoculture experiments, 3D microfluidic chip coculture, and in vivo Matrigel plug assays in mice. It was authored by Jialin Zhong and last updated on 2026-05-07.

Use Cases

• Analyze time-dependent secretion profiles of Activin A based on ELISA data mentioned in the description
• Model the regulatory effect on VEGFR1/VEGFR2 balance in endothelial cells based on protein expression profiles
• Study the suppression of SMAD2/3 phosphorylation based on ALK4 inhibition and knockdown experiments
• Validate functional vascular maturation based on 3D microfluidic chip and in vivo Matrigel plug assay results

Strengths

• Includes integrated experiments from in vitro assays to in vivo mouse models, as described
• Covers a 14-day time course for in vivo assays, as indicated by the 7-day and 14-day endpoints
• Released under the CC-BY-NC-4.0 license, specifying permissible reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

figshare

Collection Method

Integrated laboratory experiments including ELISA, protein profiling, cell culture, and animal models.

Freshness

Last updated 2026-05-07 07:02:50; freshness should be verified