DelNS1 Influenza Vaccine Preclinical Data for Mice and Hamsters

A thesis dataset from 2026 supporting immunological characterization of novel DelNS1 live attenuated influenza vaccines. Ying Liu provides raw measurements from animal models, including viral titers, antibody levels, and T cell frequencies. The data is contained in a single Excel file with worksheets organized by thesis chapter.

Use Cases

• Compare vaccine immunogenicity based on serum neutralizing antibody titers mentioned in the description
• Analyze mucosal immune responses based on IgA levels in the respiratory tract
• Evaluate protective efficacy based on body weight changes and viral titers after challenge
• Study tissue-resident memory T cell induction based on CD4+/CD8+ T cell frequencies in lungs

Strengths

• Data is structured by thesis chapter, facilitating navigation
• Includes measurements from two distinct animal models (BALB/c mice and hamsters)
• Contains data for two vaccine candidates (trivalent seasonal and monovalent H5N1)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 80.5 KB size indicates a limited scope of data

Provenance

Source

figshare

Collection Method

Experimental measurements collected during preclinical vaccine evaluation.

Freshness

Last updated 2026-04-29 05:23:52; freshness should be verified