Mouse Gpr56 Knock-in Phenotype Data Supporting PNAS Manuscript

514.1 KB of supporting data for a PNAS manuscript on the Gpr56 gene. Frank Kwarcinski published this Excel file in April 2026 to accompany research on a Gpr56 H381S knock-in mouse model. The data underpins findings on five defective phenotypes and distinct signaling pathways.

Use Cases

• Analyze the correlation between the Gpr56 H381S mutation and specific phenotype metrics for male fertility and cerebellar formation.
• Compare experimental data across the five defective phenotypes (e.g., fertility, cerebellar formation, cardiomyocyte homeostasis) to validate signaling pathway dependencies.
• Use the supporting figure and table data to replicate statistical analyses or generate visualizations for the original PNAS manuscript findings.

Strengths

• Data is directly linked to a peer-reviewed PNAS manuscript, providing authoritative context.
• The 514.1 KB Excel file contains structured tabular data for figures and tables, facilitating direct analysis.

Limitations

• The dataset's small size (514.1 KB) indicates limited scope, likely containing summary statistics rather than raw experimental data.
• Without access to specific column names or row counts, the granularity and completeness of the phenotypic measurements are unknown.
• The data is static and tied to a single 2026 publication, with no indication of ongoing updates or expansion.

Provenance

Source

Frank Kwarcinski, via the figshare repository.

Collection Method

Data generated from laboratory studies of a genetically engineered Gpr56 H381S knock-in mouse model.

Freshness

Last updated in April 2026, representing a recent snapshot for the associated publication.