Sirtuin Protein Catalytic Mechanism Data from X-ray Diffraction Experiments

Supporting data for crystallographic experiments investigating the catalytic mechanism of Sirtuin protein using monochromatic and polychromatic X-ray diffractions. The dataset includes files from experiments with a photocaged compound designed for crystallographic application. It was authored by Nan Zhang and last updated on April 29, 2026.

Use Cases

• Validate photocaged compound stability in crystallographic experiments based on the described UV irradiation release mechanism.
• Analyze intermediate protein structures based on the mention of low data quality and cofactor occupancy.
• Study enzyme-substrate recognition and binding based on the description of the released native compound being effectively bound by protein.

Strengths

• Dataset is 1.1 MB, indicating a manageable download size.
• Files are provided in multiple formats (XML, TXT, PAR, TEMP, MNOVA, INFO), suggesting diverse raw data types.
• Last updated date is April 29, 2026, indicating recent maintenance.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Data generated from crystallographic experiments using a synthesized photocaged compound.

Freshness

Last updated 2026-04-29 05:25:42; freshness should be verified.