Supporting Data for Neuroblastoma Tumor-Stroma Crosstalk Study

Supporting data for a 2026 study on MYCN-amplified neuroblastoma cells reprogramming bone marrow mesenchymal stem cells. The dataset, authored by Sau Yin Nansen Lam and shared under a CC-BY-NC-4.0 license, likely contains molecular data related to VEGF-A signaling and miR-15a-5p suppression. It was last updated on June 2, 2026, on the figshare platform.

Use Cases

• Validate findings on NOX4/HIF-1α-mediated VEGF-A signaling based on the described molecular mechanisms.
• Train models to predict angiogenic outcomes based on features related to bone marrow mesenchymal stem cell reprogramming.
• Analyze correlations between miR-15a-5p expression levels and tumor or stromal component activity mentioned in the study.
• Benchmark computational methods for identifying dual anti-angiogenic and anti-tumor therapeutic targets.

Strengths

• Data is associated with a specific, peer-reviewed study hypothesis on a promising therapeutic strategy.
• Shared under a clear, open license (CC-BY-NC-4.0) for non-commercial reuse.
• Last update timestamp (2026-06-02) is precisely recorded, indicating recent availability.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.
• Description metadata is limited; actual data quality and completeness require manual inspection.

Provenance

Source

figshare

Collection Method

Likely generated as supplementary material for the associated academic study.

Freshness

Last updated 2026-06-02 06:04:07; freshness should be verified for ongoing research.