Tetrazole Photoaffinity Probe Enrichment Data for Gut Microbiota Carbohydrate Metabolism

A 2.6 MB dataset from figshare, last updated June 3, 2026, containing chemoproteomic enrichment profiles from a suite of monosaccharide-bearing probes. The data, authored by Jack Russo, captures carbohydrate-associated protein engagement in defined bacterial cultures and human fecal lysates. It is designed to complement abundance-based proteomics by reporting on glycan-processing networks.

Use Cases

• Profiling glycoside hydrolase (GH) activity in gut microorganisms based on probe enrichment data.
• Studying protein engagement networks for carbohydrate metabolism based on tetrazole probe enrichment.
• Comparing glycan-associated protein profiles between defined bacterial cultures and complex human fecal lysates.
• Investigating the functional bias of enrichment profiles toward glycan-processing modules under different growth conditions.

Strengths

• Dataset size is 2.6 MB, indicating a focused and manageable download.
• The description details a specific application for studying carbohydrate-active enzymes (CAZymes) in gut microbiota.
• The data is licensed under CC-BY-NC-4.0, clarifying terms of use.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The description does not specify the exact number of probes in the suite or the number of experimental replicates.

Provenance

Source

figshare

Collection Method

Likely generated through chemoproteomic experiments using synthesized 2,5-tetrazole photoaffinity probes.

Freshness

Last updated 2026-06-03 03:03:54; freshness should be verified.