Synthesis Data for Cyclopropane-Fused Tetrahydropyridazines via Tandem Annulation

Dhinaakaran Murali Mohan published data on a metal-free tandem annulation reaction between coumarin-derived hydrazones and an allenyl sulfonium salt. The dataset, last updated on 2026-05-13, is a 22.6 MB ZIP file. It likely contains experimental results for synthesizing cyclopropane-fused 1,4,5,6-tetrahydropyridazines.

Use Cases

• Benchmarking new synthetic routes based on the described metal-free tandem annulation.
• Training predictive models for reaction outcomes based on the broad substrate range mentioned.
• Analyzing functional-group tolerance in organic synthesis based on the described method.

Strengths

• Dataset size is 22.6 MB, indicating a substantial amount of experimental data.
• The described method uses a bench-stable reagent, suggesting reproducible experimental conditions.
• The description mentions excellent functional-group tolerance and a broad substrate range.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect the specific experimental bias inherent to the single research project.

Provenance

Source

Dhinaakaran Murali Mohan via figshare

Collection Method

Likely contains experimental data from a synthetic chemistry study.

Freshness

Last updated 2026-05-13 03:35:06.