IVF/ICSI Cycle Outcomes with Estradiol Drop Analysis

A 15.4 KB document by Lara Janssens, last updated in March 2026, analyzes the impact of a drop in serum estradiol levels after GnRH antagonist administration on clinical outcomes in IVF/ICSI cycles. The study found this estradiol drop was associated with lower ongoing pregnancy, live birth, and cumulative live birth rates. It suggests estradiol monitoring could help identify cycles with an increased risk of less favorable outcomes.

Use Cases

• Modeling the relationship between estradiol drop and cumulative live birth rates based on the study's findings.
• Investigating the influence of gonadotropins with LH activity on estradiol levels during ovarian stimulation.
• Analyzing the correlation between serum LH decrease after GnRH antagonist administration and clinical outcomes.

Strengths

• Data is licensed under CC-BY-4.0, allowing for open sharing and adaptation.
• The study focuses on a specific clinical phenomenon (estradiol drop) with clear outcome measures (pregnancy and live birth rates).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 15.4 KB, indicating limited scope.

Provenance

Source

Lara Janssens via figshare

Collection Method

Likely contains clinical study data from in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles.

Freshness

Last updated 2026-03-18 05:34:50; freshness should be verified.