Cyp26c1 Reporter Line for Retinoic Acid Signalling in Zebrafish Development

A 15.2 KB DOCX file describes a novel transgenic reporter line for the zebrafish cyp26c1 gene, a key regulator of retinoic acid metabolism. The resource, created by Rosana Reyes-Pinto and last updated in May 2026, provides a tool for tracing cyp26c1-expressing cells with cellular resolution in developing embryos.

Use Cases

• Visualizing spatiotemporal dynamics of cyp26c1 expression based on the reporter line's cellular resolution
• Investigating the effects of exogenous retinoic acid manipulation on gene expression patterns within the retina
• Studying the role of cyp26c1 in specific developmental structures like the telencephalon and pharyngeal arches
• Tracing and manipulating cyp26c1-expressing cell populations during zebrafish embryogenesis

Strengths

• The reporter line is described as faithfully mirroring endogenous cyp26c1 expression, suggesting high biological relevance
• Expression is characterized with cellular resolution, indicating a high level of detail
• The dataset is openly licensed under CC-BY-4.0

Limitations

• The dataset is very small (15.2 KB), indicating limited scope and likely containing only descriptive documentation
• Column-level documentation and sample data are unavailable, making field semantics unclear
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Created through a screen of a gal4-based gene and enhancer trap collection to isolate the transgenic line.

Freshness

Last updated 2026-05-26 08:31:31; freshness should be verified