Pediatric Prader-Willi Syndrome fMRI Data for 68 Subjects

Table 1_Aberrant local and global neural activation patterns in pediatric Prader–Willi syndrome is a neuroimaging dataset from a study by Jie Liu, last updated in April 2026. It contains data from 35 pediatric patients with Prader–Willi syndrome and 33 healthy controls, analyzing amplitude of low-frequency fluctuations, regional homogeneity, and functional connectivity. The dataset is stored as a 57.9 KB DOCX file on figshare under a CC-BY-4.0 license.

Use Cases

• Compare local neural activation patterns based on ALFF and ReHo metrics between patient and control groups.
• Analyze functional connectivity networks based on seed-based whole brain FC analysis mentioned in the description.
• Investigate correlations between brain activation patterns and developmental scores based on the Griffiths Developmental Scales.
• Identify potential physiological indicators for cognitive abnormalities based on decreased neural activation patterns.

Strengths

• Includes data from a defined cohort of 68 subjects (35 patients, 33 controls).
• Analyzes multiple neural metrics: ALFF, ReHo, and seed-based functional connectivity.
• Correlates neural data with clinical developmental scores (Griffiths Developmental Scales).

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is very small at 57.9 KB, indicating limited scope, likely a summary table.
• Data is provided in a DOCX format, which may require extraction for computational analysis.

Provenance

Source

Jie Liu via figshare.

Collection Method

fMRI data analysis from a study comparing pediatric PWS patients and healthy controls.

Time Range

Study period not specified.

Freshness

Last updated 2026-04-15 04:37:04; freshness should be verified.

Geography

Geographic coverage not specified.