Mouse Gut Microbiota Composition and Energy Metabolism After Acute High-Intensity Exercise

A study investigating dynamic alterations in gut microbiota following a 30-minute high-intensity treadmill run in BALB/c and C57BL/6 mice. Colonic content samples were collected at 0, 30, and 60 minutes post-exercise for 16S rRNA gene sequencing. The dataset, authored by Ruolin Gao and last updated in April 2026, is shared under a CC-BY-4.0 license.

Use Cases

• Analyzing strain-specific gut microbiota responses to acute exercise based on the comparison of BALB/c and C57BL/6 mice.
• Investigating temporal dynamics of microbial diversity based on samples collected at three post-exercise time points.
• Studying the relationship between the Bacteroidetes/Firmicutes ratio and energy metabolism based on the reported post-exercise elevation.
• Identifying exercise-responsive microbial taxa like Muribaculum based on its identification as a key genus across time points.

Strengths

• Includes temporal data with samples collected at 0, 30, and 60 minutes post-exercise.
• Compares two distinct mouse strains (BALB/c and C57BL/6), allowing for strain-specific analysis.
• Data is shared under a permissive CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (18.2 KB), indicating limited scope, likely containing summary results rather than raw sequencing data.

Provenance

Source

figshare, author Ruolin Gao.

Collection Method

16S rRNA gene sequencing of colonic content from mice after a controlled treadmill exercise protocol.

Time Range

Samples collected immediately, 30 minutes, and 60 minutes post-exercise.

Freshness

Last updated 2026-04-22 16:31:40; freshness should be verified.

Geography

Laboratory study, location unknown.