Adverse Outcomes for Autistic People: An Umbrella Review Across Health and Social Domains

An umbrella review synthesizing evidence from 134 systematic, meta-analytic, and narrative reviews on outcomes associated with autism. The work aggregates findings across three domains: mental health, physical health, and social and lifestyle factors. Blandine French authored this review, which was last updated in May 2026.

Use Cases

• Identify priority areas for clinical intervention based on the reported clusters of adverse outcomes.
• Inform public health policy and service planning for autistic populations based on review-level evidence.
• Guide future research directions by highlighting outcome domains with varying evidence strength.
• Support meta-research on autism by providing a cross-domain synthesis of existing review findings.

Strengths

• Synthesizes findings from 134 reviews, providing a broad evidence base.
• Methodologically rigorous, using dual screening, multi-reviewer extraction, and established quality appraisal tools.
• Covers a wide range of adverse outcomes across mental health, physical health, and social/lifestyle domains.

Limitations

• The underlying data is a 93.4 KB DOCX file, suggesting a limited scope primarily containing the review manuscript rather than raw data.
• Column-level documentation is absent; field semantics must be inferred from the narrative text.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Systematic umbrella review of published systematic, meta-analytic, and narrative reviews.

Time Range

Reviews searched from database inception to June 2024.

Freshness

Last updated 2026-05-11 13:51:38; freshness should be verified.