Mouse Study Data on Akkermansia muciniphila and SARS-CoV-2 Immune Response

13.1 KB of tabular data from a study investigating the gut-lung axis during SARS-CoV-2 infection. The dataset, authored by Gi-Cheon Kim and shared under CC-BY-4.0, contains results from experiments on K18-hACE2 transgenic mice, including measurements of weight loss, lung pathology, and immune cell phenotypes. It was last updated on March 18, 2026.

Use Cases

• Analyze correlations between microbial enrichment and host immune outcomes based on the described reduction in gut diversity and enrichment of A. muciniphila.
• Model the protective effects of probiotic administration based on described metrics like reduced weight loss and improved lung histopathology.
• Investigate mucosal immune priming based on described features like elevated Th2/Th17 cytokines and expansion of tissue-resident memory T cells.

Strengths

• Data is from a controlled experimental study using a transgenic mouse model (K18-hACE2).
• Dataset is shared under a permissive CC-BY-4.0 license.
• Last update was recorded as March 18, 2026.

Limitations

• Dataset is very small at 13.1 KB, indicating limited scope.
• Row count and column-level documentation are unknown, requiring manual inspection after download.
• Data is derived from a specific animal model, which may limit direct translation to human biology.

Provenance

Source

figshare, author Gi-Cheon Kim

Collection Method

Experimental data from a study administering live A. muciniphila to mice infected with SARS-CoV-2 variants.

Freshness

Last updated 2026-03-18 07:41:59