Alicyclobacillin 24: A Class III Bacteriocin from Alicyclobacillus Acidoterrestris

Alicyclobacillin 24 is the first functional Class III bacteriocin identified from the thermoacidophilic spoilage bacterium Alicyclobacillus acidoterrestris DSM 3922T. The 658.6 KB document by Inês Carvalho Leonardo, last updated May 2026, details its discovery, heterologous expression, and characterization. Ali24 exhibits a narrow antibacterial spectrum effective against spoilage-associated Alicyclobacillus species under acidic pH and moderate heating up to 50°C.

Use Cases

• Screening for novel bacteriocins based on genome analysis of Alicyclobacillus species mentioned in the description
• Evaluating antimicrobial stability for food preservation based on activity under acidic pH and heating up to 50°C
• Studying membrane-associated antimicrobial mechanisms based on SYTO9/propidium iodide staining assays described
• Developing sustainable biocontrol agents for the food industry based on the narrow anti-spoilage spectrum of Ali24

Strengths

• The dataset is a detailed research document (658.6 KB) describing the first functional Class III bacteriocin from A. acidoterrestris
• Functional characterization includes activity tests under industrially-relevant conditions like acidic pH and heating up to 50°C
• Available under a permissive CC-BY-4.0 license for reuse

Limitations

• The dataset is a single DOCX file; its internal structure and any potential tabular data are not described
• Row count and column-level documentation are unknown, limiting suitability assessment for computational analysis
• The 658.6 KB size indicates a limited scope, likely containing the research manuscript rather than large-scale experimental data

Provenance

Source

figshare

Collection Method

Likely contains research data and analysis from a study exploring bacteriocin production in Alicyclobacillus acidoterrestris DSM 3922T.

Freshness

Last updated 2026-05-01 05:28:05