Neuroimaging Metrics for 101 Nasopharyngeal Carcinoma Patients Pre- and Post-Radiotherapy

101 nasopharyngeal carcinoma patients (45 pre-radiotherapy and 56 post-radiotherapy) underwent 3T MRI scans to assess glymphatic system changes. The dataset, authored by Lingling Deng and last updated in May 2026, contains derived imaging metrics including choroid plexus volumes and free-water fraction values in white matter tracts. Results show significant bilateral choroid plexus enlargement and elevated free-water fraction in post-radiotherapy patients.

Use Cases

• Modeling radiation dose relationships with choroid plexus volume based on reported Spearman correlations.
• Analyzing changes in white matter free-water fraction in specific tracts (e.g., corticospinal tract) post-radiotherapy.
• Investigating associations between choroid plexus enlargement and free-water fraction elevation as indicators of glymphatic dysfunction.

Strengths

• Includes a cohort of 101 patients with clear pre- and post-radiotherapy subgroups (45 and 56 patients).
• Reports specific volumetric measurements (e.g., total choroid plexus volume: 2560.56 ± 636.72 mm³) and statistical correlations (r values up to 0.599).
• Results are adjusted for covariates including age, gender, and intracranial volume.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for specific modeling tasks.
• The cross-sectional study design limits causal inference regarding radiotherapy effects.

Provenance

Source

Lingling Deng via figshare.

Collection Method

Cross-sectional cohort study using 3T MRI (T1-weighted and diffusion tensor imaging) with automated segmentation and analysis.

Time Range

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Freshness

Last updated 2026-05-04 05:30:32; freshness should be verified.

Geography

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