Antibiotic Resistance and Biofilm Capacity of Oral Bacteria in Healthy and Caries Patients

David L. Auer's dataset, last updated April 2026, contains results from a study comparing antimicrobial susceptibility and biofilm-forming capacity of supragingival bacterial isolates. The data covers 319 bacterial isolates from 40 participants, tested for antibiotic resistance via disk diffusion and Etest methods and for biofilm formation via crystal violet staining. The findings highlight differences in resistance and biofilm patterns between healthy individuals and those with active caries.

Use Cases

• Compare antibiotic susceptibility patterns between bacterial taxa based on the resistance testing results described.
• Analyze the association between biofilm-forming capacity and antibiotic resistance among obligate anaerobes based on the study's findings.
• Model differences in microbial profiles between healthy and caries-affected individuals based on the group comparisons for specific species.
• Investigate ecological shifts in oral biofilms related to disease state as indicated by the isolate-level observations.

Strengths

• Includes 319 bacterial isolates from 40 participants, providing a basis for statistical analysis.
• Uses multiple standardized testing methods: disk diffusion, Etest, β-lactamase testing, and crystal violet staining for biofilm quantification.
• Statistical analyses account for the clustering of isolates within individuals, a noted methodological strength.

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment and requires manual inspection after download.
• The dataset is very small at 31.6 KB, indicating limited scope and likely summary-level results rather than raw experimental data.

Provenance

Source

David L. Auer via figshare

Collection Method

Bacterial isolates from participants were tested for antibiotic susceptibility and biofilm formation using laboratory methods described.

Time Range

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Freshness

Last updated 2026-04-24 12:57:48; freshness should be verified.

Geography

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