Table 1_Antimicrobial activity of ceftolozane/tazobactam, imipenem/relebactam, and compara

A collection of 4,950 clinical isolates of Enterobacterales and Pseudomonas aeruginosa from patients in Kuwait, Qatar, the United Arab Emirates, and Oman between 2020 and 2024. The dataset, authored by Mark G. Wise and last updated in 2026, reports in vitro susceptibility results for ceftolozane/tazobactam, imipenem/relebactam, and comparator antimicrobial agents. Molecular characterization data for acquired β-lactamases is included for most non-susceptible isolates.

Use Cases

• Compare the in vitro activity of newer β-lactam/β-lactamase inhibitor combinations against Gram-negative pathogens based on reported susceptibility percentages.
• Analyze the prevalence of metallo-β-lactamases (e.g., NDM) in resistant isolates based on molecular characterization data.
• Investigate regional antimicrobial resistance trends in the Arabian Gulf based on data collected from multiple countries over five years.
• Assess the activity of ceftolozane/tazobactam against meropenem-resistant Pseudomonas aeruginosa based on the reported 66.9% inhibition rate.

Strengths

• Contains 4,950 clinical isolates (3,603 Enterobacterales and 1,347 Pseudomonas aeruginosa).
• Provides molecular characterization data for acquired β-lactamases in most non-susceptible isolates.
• Covers a five-year time range (2020–2024) and includes data from five clinical laboratories across four Arabian Gulf countries.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic bias inherent to the specific hospitals and laboratories in the Arabian Gulf region.

Provenance

Source

figshare

Collection Method

Isolates were collected from patients with bloodstream, intra-abdominal, lower respiratory tract, and urinary tract infections. MICs were determined by CLSI broth microdilution.

Time Range

2020–2024

Freshness

Last updated 2026-05-12 05:27:04

Geography

Arabian Gulf region (Kuwait, Qatar, United Arab Emirates, Oman)