Apocynum Venetum Extract Effects on Diabetic Kidney Disease in Mouse Model

A dataset from figshare containing experimental results on the effects of Apocynum venetum L. leaves extract (AVLE) on diabetic kidney disease. The data likely includes serum and urine parameters, histopathology results, and proteomic analysis from a 12-week study using db/db mice and HK-2 cells. The dataset was authored by Guohua Shi and last updated on 2026-05-07.

Use Cases

• Analyze the relationship between AVLE treatment and renal function parameters based on serum and urine measurements.
• Investigate protein expression changes related to fibrosis and ferroptosis based on proteomic analysis results.
• Validate the role of the Nrf2/HO-1 signaling pathway in renal protection based on experimental verification data.

Strengths

• The dataset is associated with a detailed experimental methodology involving both in vivo (db/db mice) and in vitro (HK-2 cells) models.
• Proteomic analysis identified 60 metabolites absorbed into serum, providing a basis for mechanistic exploration.
• The dataset is licensed under CC-BY-4.0, allowing for open reuse and sharing.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (29.4 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Experimental data from pharmacological study using animal models and cell cultures.

Freshness

Last updated 2026-05-07 05:42:32; freshness should be verified.