NHANES Inflammatory Biomarkers and Cataract Surgery Associations, 2005-2008

8,194 participants from the 2005–2008 NHANES cycles were analyzed to investigate links between inflammatory biomarkers and cataract surgery history. The study by Jingjing Ding, validated with a clinical cohort, found positive linear associations for log-transformed AISI, NAR, and MAR with cataract surgery prevalence. The dataset, last updated in April 2026, is a 22.4 KB document containing the study's tabular results.

Use Cases

• Validate associations between inflammatory indices like MAR and cataract risk based on the NHANES analysis.
• Conduct subgroup analyses for age, gender, or health conditions based on the described methodology.
• Assess the predictive utility of biomarkers for cataract surgery using ROC curve analysis as described.
• Replicate sensitivity analyses to test the robustness of biomarker-cataract associations.

Strengths

• Includes data from 8,194 participants from a nationally representative survey (NHANES).
• Findings were validated using a separate clinical cohort, as stated in the description.
• The study employed multivariate logistic regression, RCS, and subgroup analyses for robustness.

Limitations

• The dataset is a 22.4 KB DOCX file; the underlying tabular data's structure and column definitions are not provided.
• Row count for the primary analytical dataset is unknown, limiting scale assessment.
• The discriminatory ability of the biomarkers (AUC=0.592 for Ln-MAR) was described as modest.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES) database and a clinical cohort.

Collection Method

Cross-sectional analysis of NHANES 2005-2008 cycles with subsequent clinical validation.

Time Range

2005-2008 for the primary NHANES analysis.

Freshness

Last updated 2026-04-28 04:29:19

Geography

United States (NHANES).