Serum Uric Acid and Gestational Diabetes Risk in 44,609 Pregnant Women

A retrospective cohort study of 44,609 singleton pregnant women from three medical centers between January 2018 and June 2024. The data likely contains serum uric acid levels measured before 20 weeks of gestation and outcomes for gestational diabetes mellitus (GDM), GDM requiring insulin, and GDM with pre-eclampsia. The study was authored by Qiong Li and published on figshare under a CC-BY-4.0 license.

Use Cases

• Modeling the nonlinear relationship between uric acid and GDM risk based on the described threshold effect at 240 μmol/L.
• Training classifiers to predict GDM requiring insulin therapy (GDMA2) based on early-pregnancy biomarkers.
• Conducting subgroup analyses on GDM risk factors using the described demographic and clinical variables.
• Validating causal inferences for uric acid and GDM using the described Mendelian randomization results.

Strengths

• Large cohort of 44,609 pregnant women from three medical centers.
• Study period spans over six years, from January 2018 to June 2024.
• Analysis includes multiple statistical methods and a Mendelian randomization component for causal inference.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic or institutional bias inherent to the three medical centers.

Provenance

Source

figshare, author Qiong Li.

Collection Method

Retrospective cohort study from three medical centers.

Time Range

January 2018 to June 2024.

Freshness

Last updated 2026-04-17 05:20:43; freshness should be verified.

Geography

Likely China, based on author name and common medical terminology, but not explicitly stated.