Table 1_Association between systemic immune-inflammation index(SII) and all-cause and card

1,084 heart failure patients were enrolled in a retrospective cohort study between January 2022 and June 2023. The dataset, shared by Junlan Zhang on figshare, analyzes the association between the systemic immune-inflammation index (SII) and all-cause and cardiovascular mortality, with follow-up until July 2025. Results indicate a significant association between elevated SII and increased all-cause mortality risk, particularly among smokers.

Use Cases

• Predicting all-cause mortality risk in heart failure patients based on systemic immune-inflammation index (SII) values.
• Investigating the mediating role of NT-proBNP and left ventricular ejection fraction (LVEF) in the SII-mortality relationship.
• Conducting subgroup analysis to identify patient characteristics, such as smoking status, that modify the effect of SII on mortality.
• Validating the SII as a prognostic biomarker using Cox proportional hazards models and restricted cubic splines.

Strengths

• Contains data for 1,084 heart failure patients, providing a substantial clinical cohort.
• Follow-up was conducted until July 2025, offering a defined longitudinal observation period.
• Analysis includes fully adjusted hazard ratios, confidence intervals, and mediation percentages (e.g., NT-proBNP mediated 35.8%).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data reflects a single-center study, which may limit generalizability.

Provenance

Source

Junlan Zhang

Collection Method

Retrospective cohort study of patients hospitalized for heart failure.

Time Range

Patient enrollment from January 2022 to June 2023, with follow-up until July 2025.

Freshness

Last updated 2026-04-24 13:07:02; freshness should be verified.

Geography

Single-center study; specific location is unknown.