Naples Prognostic Score and Cognitive Function in Older Adults: NHANES 2011-2014

2011-2014 data from 2,595 participants aged 60+ in the National Health and Nutrition Examination Survey (NHANES) investigating the association between the Naples Prognostic Score (NPS) and cognitive impairment. The dataset was authored by Hao Yang and includes validation in an independent clinical cohort of 189 patients with Alzheimer's disease and vascular dementia.

Use Cases

• Train models to predict cognitive impairment risk based on systemic inflammatory-metabolic scores.
• Analyze dose-response relationships between composite biomarker scores and executive function.
• Validate prognostic scoring systems across different dementia subtypes like Alzheimer's disease and vascular dementia.

Strengths

• Includes data from 2,595 participants from a nationally representative survey (NHANES).
• Validated findings in an independent clinical cohort of 189 diagnosed patients.
• Uses three established cognitive function tests (CERAD, CFDAST, CFDDS).

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The primary data file is a 28.9 KB DOCX, suggesting the dataset may contain summary results rather than raw participant-level data.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES) and an independent clinical cohort.

Collection Method

Secondary analysis of survey data and clinical validation cohort.

Time Range

2011-2014

Freshness

Last updated 2026-03 17 13:05:34.

Geography

United States