Vitamin D Status and Biomarkers in 503 Patients with Type 2 Diabetes

A cross-sectional study of 503 patients with type 2 diabetes, investigating associations between serum 25-hydroxyvitamin D levels and calcium metabolism, inflammation, and thyroid autoimmunity. The dataset was published by Nannan Lv on figshare in June 2026 under a CC-BY-4.0 license. It reports that 83.7% of the cohort had vitamin D deficiency (<20 ng/mL).

Use Cases

• Modeling the relationship between vitamin D levels and parathyroid hormone (PTH) based on reported significant correlations.
• Investigating links between vitamin D status and inflammatory markers like hsCRP, which peaked in the moderate deficiency group.
• Analyzing complex associations between vitamin D and thyroid autoantibodies (TPOAb/TGAb), which showed opposing relationships.
• Studying the prevalence of vitamin D deficiency in a type 2 diabetes population, reported at 83.7%.

Strengths

• Includes data from 503 patients, providing a substantial clinical cohort.
• Stratifies patients into four clinically relevant vitamin D status groups.
• Reports specific statistical findings, such as P-values for associations with PTH, calcium, and thyroid antibodies.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The data is contained in a 23.8 KB DOCX file, suggesting limited scope and likely summary statistics rather than raw patient-level data.

Provenance

Source

Nannan Lv via figshare.

Collection Method

Cross-sectional clinical study enrolling 503 patients with type 2 diabetes.

Freshness

Last updated 2026-06-04 04:27:29; freshness should be verified.