NODDI Neuroimaging and Cognitive Scores for 90 Nasopharyngeal Carcinoma Patients

90 nasopharyngeal carcinoma patients with radiation-induced temporal lobe injury underwent neuroimaging and cognitive assessment. The dataset, authored by Weike Zeng and last updated in June 2026, includes neurite orientation dispersion and density imaging (NODDI) parameters and Montreal Cognitive Assessment (MoCA) scores. It was used to evaluate associations between imaging biomarkers and cognitive impairment.

Use Cases

• Train models to predict cognitive impairment based on NODDI-derived parameters like intra-neurite volume fraction (ICVF).
• Analyze correlations between neuroimaging biomarkers and clinical assessment scores such as the MoCA.
• Benchmark diagnostic performance of different diffusion MRI metrics for radiation-induced brain injury.

Strengths

• Includes data from 90 patients in a prospective study design.
• Reports specific statistical results, such as an AUC of 0.869 for ICVF in discriminating cognitive impairment.
• Released under a CC-BY-4.0 license, permitting open reuse with attribution.

Limitations

• The dataset is small at 677.9 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Prospective clinical study involving structural MRI, diffusion-weighted imaging, and cognitive assessments.

Freshness

Last updated 2026-06-01 04:18:56; freshness should be verified.