Frailty Transition and Dementia Risk in Two Longitudinal Cohorts

Two longitudinal cohort studies analyzed 8,353 participants to assess the association between transitions in frailty status and dementia risk. The data includes hazard ratios and confidence intervals from Cox models evaluating transitions between robust, pre-frail, and frail states. The findings were published by author Mingrui Liu.

Use Cases

• Analyze hazard ratios (HR) and confidence intervals (95% CI) to quantify dementia risk associated with frailty transitions.
• Model transitions between robust, pre-frail, and frail status categories using Cox proportional hazards methods.
• Validate the association of frailty progression with increased dementia risk using the reported p-values and cohort data.

Strengths

• Analysis includes 8,353 participants from two prospective cohorts.
• Results are supported by sensitivity analyses confirming robustness.
• Data is shared under a permissive CC BY 4.0 license.

Limitations

• Small dataset size of 65.5 KB suggests limited raw data or only summary statistics.
• Dementia outcome was ascertained by self-reported physician diagnosis, which may introduce measurement bias.
• Specific column structure, row count, and individual-level data are unknown.

Provenance

Source

figshare, authored by Mingrui Liu.

Collection Method

Analysis of two prospective longitudinal cohorts using Frailty Index assessments and Cox proportional hazards models.

Time Range

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Freshness

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Geography

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