Clinical Obesity, Arterial Stiffness, and Cerebral Small Vessel Disease in 2,011 Adults

2,011 adults from the Kailuan Cohort underwent brain MRI and obesity assessments from 2021 to 2024. This cross-sectional study by Mengmeng Bai investigates associations between clinical obesity, arterial stiffness, and cerebral small vessel disease (cSVD) imaging markers. Results show arterial stiffness mediates the relationship between obesity and cSVD.

Use Cases

• Train predictive models for cerebral small vessel disease (cSVD) risk based on clinical obesity indicators.
• Analyze the mediating role of arterial stiffness in the obesity-cSVD relationship using statistical methods.
• Study associations between obesity and specific brain imaging markers like perivascular spaces (PVS) and white matter hyperintensities (WMH).

Strengths

• Includes 2,011 participants with a mean age of 53.7 years and a balanced sex distribution (49.8% male).
• Data collection involved brain magnetic resonance imaging (MRI) scans and clinical obesity assessments.
• Analysis adjusted for multiple covariates including age, sex, smoking history, and lipid levels.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small in scale (687.9 KB), suggesting limited raw data or a summary document.

Provenance

Source

Multimodal Imaging Study based on the Kailuan Cohort.

Collection Method

Cross-sectional study analyzing adults who underwent brain MRI and obesity assessments.

Time Range

Data collected from 2021 to 2024.

Freshness

Last updated 2026-06-02 04:21:30; freshness should be verified.

Geography

Likely based on the Kailuan Cohort in China; specific geography not stated.