TCBI and CVD Risk in Aging Cohorts from CHARLS and ELSA

6,013 participants from two large aging cohorts were analyzed to assess the association between a composite metabolic-nutritional index and incident cardiovascular disease. The dataset contains results from Cox models and restricted cubic spline analyses, showing a significant association for the continuous TCBI variable. Author Peijian Wang published this analysis under a CC-BY-4.0 license on figshare in April 2026.

Use Cases

• Validate the triglyceride-cholesterol-body weight index (TCBI) as a predictor of cardiovascular disease based on longitudinal cohort data.
• Compare the predictive performance of TCBI against conventional risk factors based on discrimination and reclassification metrics mentioned in the results.
• Conduct subgroup analyses on incident CVD risk based on the prespecified subgroups referenced in the methods.
• Model non-linear relationships between metabolic indices and disease outcomes using restricted cubic spline analysis techniques described.

Strengths

• Analysis includes 6,013 participants from two distinct cohorts (CHARLS: 3,741; ELSA: 2,272).
• Data spans long-term follow-up periods (CHARLS: 2011–2018; ELSA: 2002–2018).
• Results are based on multiple modeling strategies, including Cox models and restricted cubic splines.
• The dataset is openly available under a permissive CC-BY-4.0 license.

Limitations

• The dataset is very small (21.1 KB), suggesting it contains summary results or a single table rather than raw participant-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying analytical dataset is unknown, which may limit suitability assessment.

Provenance

Source

Harmonized data from the China Health and Retirement Longitudinal Study (CHARLS) and the English Longitudinal Study of Aging (ELSA).

Collection Method

Analysis of community-dwelling adults aged 45+ free of CVD at baseline, with TCBI calculated from triglycerides, total cholesterol, and body weight.

Time Range

CHARLS: 2011–2018; ELSA: 2002–2018

Freshness

Last updated 2026-04-21 04:20:17; freshness should be verified.

Geography

China and England