BCS2.0: Bacterial Species and AMR Gene Detection Data from Clinical Samples

234.0 KB of data from a capture sequencing platform designed for rapid differential diagnosis. The dataset, authored by Amit Ranjan and last updated in April 2026, contains results from the BCS2.0 assay, which targets 894 pathogenic bacterial species and antimicrobial resistance determinants. Performance measures include limits of detection and assay reproducibility validated in plasma and urine samples.

Use Cases

• Benchmarking rapid diagnostic tools based on detection limits and reproducibility data mentioned in the description
• Analyzing concordance between sequencing assays and traditional methods like MALDI-TOF based on validation results
• Studying mixed infection profiles based on the platform's ability to detect co-infections
• Investigating antimicrobial resistance gene prevalence based on the targeted AMR determinants

Strengths

• Validated with a limit of detection of 5 colony-forming units per milliliter
• Targets a broad panel of 894 known or potential pathogenic bacterial species
• Includes data from both contrived and clinical samples in plasma and urine
• Results show concordance with MALDI-TOF and BCID assays

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is small at 234.0 KB, indicating limited scope

Provenance

Source

figshare

Collection Method

Data generated from a capture sequencing platform (BCS2.0) using designed probes against reference databases.

Time Range

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Freshness

Last updated 2026-04-20 05:23:16

Geography

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