Berberine Modulation of Virulence Gene Expression in MRSA

Quantitative Real-time PCR data showing the effect of berberine on virulence gene expression in methicillin-resistant Staphylococcus aureus. The dataset was created by Fangfang Zhou and last updated on 2026-04-28. It is shared under a CC-BY-4.0 license.

Use Cases

• Analyze the inhibitory effect of berberine on the Agr quorum-sensing system based on qRT-PCR data mentioned in the description
• Correlate gene expression changes with phenotypic outcomes like hemolytic activity and biofilm formation based on described assays
• Model the relationship between Agr system suppression and downregulation of specific virulence genes (hla, psmα, clfA) based on the study findings

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• File size is 10.3 KB, indicating a focused and manageable dataset.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Likely contains experimental data from qRT-PCR and phenotypic assays described in the associated study.

Freshness

Last updated 2026-04-28 05:28:00; freshness should be verified.