Bone Marrow Cellular Profiles in Diabetic Patients with Limb Ischemia

Seventy-four patients with chronic limb-threatening ischemia were analyzed in a retrospective study spanning 16 years. The data, published by Dominika Sojakova in 2026, shows associations between statin therapy, diabetes severity scores, and CD34+ cell percentages in bone marrow. Results suggest statins may modify the bone marrow microenvironment rather than increase absolute progenitor cell numbers.

Use Cases

• Correlating statin use with CD34+ cell percentages based on immunophenotyping data mentioned in the description
• Analyzing the relationship between diabetes severity (DCSI scores) and bone marrow cellular composition
• Investigating associations between diabetic parameters (type, duration, HbA1c) and hematopoietic cell populations like lymphocytes and monocytes

Strengths

• Data is derived from a 16-year retrospective observational study of autologous cell therapy patients.
• Analysis includes 74 patient records with hematological and immunophenotyping outcomes.
• Results are linked to specific diabetes parameters and medication use, including statins and oral antidiabetics.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 27.0 KB file size suggests a very limited scope, likely containing summary results rather than raw patient-level data.

Provenance

Source

figshare, author Dominika Sojakova

Collection Method

Retrospective observational study analyzing patients treated with autologous cell therapy for chronic limb-threatening ischemia.

Time Range

Study period covers 16 years (specific years not provided).

Freshness

Last updated 2026-05-29 04:47:27; freshness should be verified.