Brain Metastasis in Head and Neck Cancer: Analysis of 201 Patient Cases

201 patients with head and neck squamous cell carcinoma who developed brain metastasis were analyzed in a retrospective study from three tertiary care institutions. The median survival time after brain metastasis diagnosis was 3 months, with an incidence rate of 1.1%. Junhui Yuan published this analysis under a CC-BY-4.0 license in April 2026.

Use Cases

• Modeling survival trajectories based on the reported median survival time and hazard ratios for different treatments.
• Analyzing patterns of intracranial metastasis distribution based on the counts of single vs. multiple metastases.
• Investigating the correlation between brain metastasis and lung metastasis as suggested in the conclusion.
• Comparing treatment efficacy based on hazard ratios for whole-brain radiotherapy, stereotactic radiosurgery, and surgery with radiotherapy.

Strengths

• Includes specific clinical statistics: 201 patient cases, 1.1% incidence rate, and median survival of 3 months.
• Provides detailed treatment outcome metrics with hazard ratios and confidence intervals.
• Documents metastasis distribution patterns: 65 single, 84 with 2-3, and 52 with 4+ metastases.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is contained in a 29.0 KB DOC file, indicating a very small, likely summary-level dataset.

Provenance

Source

Junhui Yuan via figshare.

Collection Method

Retrospective analysis of patient records from three tertiary care institutions.

Time Range

The median interval from initial treatment to brain metastasis diagnosis was 2.5 years, but the exact study period is not specified.

Freshness

Last updated 2026-04-13 04:31:17; freshness should be verified.

Geography

Geographic coverage of the three institutions is not specified.