CALB2 Gene Expression and Prognostic Data for Colorectal Cancer

CALB2 expression data correlated with poor prognosis in colorectal cancer patients from integrated TCGA and GEO datasets. The 10.3 KB Excel file, authored by Yibo Bian and last updated in April 2026, contains results from functional experiments on cell proliferation, migration, and tumor microenvironment remodeling. Its findings identify CALB2 as a regulator of tumor progression and immune escape.

Use Cases

• Correlating gene expression with patient prognosis based on CALB2 expression levels.
• Modeling tumor microenvironment composition based on macrophage polarization and immune cell infiltration data.
• Investigating signaling pathways in cancer based on STAT3 and CCL5 secretion mechanisms mentioned in the description.

Strengths

• Data is derived from integrated analysis of established public sources TCGA and GEO.
• Results are linked to specific functional assays like proliferation, migration, and co-culture.
• File is openly licensed under CC-BY-4.0.

Limitations

• Dataset is very small at 10.3 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Integrated analysis of TCGA and GEO datasets.

Collection Method

Functional experiments including proliferation, migration, colony formation, apoptosis assays, co-culture assays, and multiplex immunohistochemistry.

Time Range

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Freshness

Last updated 2026-04-15 05:44:12; freshness should be verified.

Geography

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