Calcium-Dependent SctV-SctW Interaction Data for Type III Secretion Switch

Data from a 2026 study by Athina G. Portaliou, published on figshare under a CC-BY-4.0 license, investigating the molecular mechanism of the bacterial type III secretion system. The dataset likely contains quantitative measurements of protein binding affinities and secretion states under varying calcium conditions. It is a small dataset, 154.7 KB in size, stored in an XLSX file.

Use Cases

• Modeling the calcium-dependent affinity switch between SctV and SctW proteins based on the described binding data.
• Analyzing the relationship between calcium concentration and the secretion hierarchy of translocators versus effectors.
• Investigating the functional impact of mutations in SctV or SctW that disrupt calcium-dependent crosstalk.

Strengths

• Data is associated with a specific, peer-reviewed research study on a defined molecular mechanism.
• Published under a permissive CC-BY-4.0 license, allowing for reuse and redistribution.
• File is in the widely accessible XLSX format, 154.7 KB in size.

Limitations

• Row count and specific column definitions are unknown, requiring manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred from the accompanying research article.
• The dataset's 154.7 KB size indicates a limited scope, likely containing summary or key experimental results rather than raw high-throughput data.

Provenance

Source

Athina G. Portaliou via figshare.

Collection Method

Likely generated from laboratory experiments measuring protein binding and secretion assays.

Freshness

Last updated 2026-05-20 13:01:57.