Calprotectin and aMMP-8 Biomarker Levels in Geriatric Inpatients

Alicia Maria Meyer-Hofmann's dataset contains biomarker measurements from gingival crevicular fluid samples collected from 30 neurogeriatric inpatients with a mean age of 79 ± 6 years. The cross-sectional study assessed levels of Calprotectin and Active Matrix Metalloproteinase-8 alongside periodontal clinical indices and systemic blood values. The data was last updated on figshare in April 2026.

Use Cases

• Correlating biomarker levels with clinical periodontal indices like Bleeding On Probing and Probing Pocket Depth
• Evaluating the feasibility of bedside biomarker collection in geriatric inpatient settings
• Comparing the diagnostic value of inflammation (Calprotectin) versus tissue degradation (aMMP-8) biomarkers
• Analyzing associations between localized periodontal processes and systemic inflammatory markers

Strengths

• Dataset includes biomarker measurements from 30 geriatric inpatients with minimal systemic inflammation (CRP < 5 mg/dL)
• Correlation benchmarks are explicitly defined (r = .10 weak, r = .30 moderate, r = .50 strong)
• Study reports specific correlation results, such as a strong correlation (rs = .521) between CP and aMMP-8

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The sample size of 30 patients is small, limiting generalizability

Provenance

Source

Alicia Maria Meyer-Hofmann

Collection Method

Cross-sectional study with GCF samples collected at bedside from neurogeriatric inpatients

Freshness

Last updated 2026-04-10 07:57:20; freshness should be verified