Table 1_Carbapenem-resistant enterobacterales in sterile body fluids: ten-year population

62 non-duplicate Carbapenem-Resistant Enterobacterales (CRE) isolates from sterile body fluids were analyzed over a ten-year period. The dataset, created by Shenyun Cao and shared on figshare, includes whole-genome sequencing results for resistance genes, virulence factors, and sequence types, paired with clinical outcome data. Klebsiella pneumoniae ST11 carrying the blaKPC-2 gene was the dominant clone, and ICU admission was significantly associated with patient mortality.

Use Cases

• Analyze the molecular epidemiology of dominant CRE clones based on sequence type and phylogenetic cluster data.
• Investigate correlations between specific resistance gene profiles and clinical outcomes based on mortality and ICU admission data.
• Study the co-occurrence of virulence factors, such as the rmpA2 gene, with multidrug resistance patterns in bacterial isolates.
• Model the genetic relatedness and transmission dynamics of hospital-acquired infections based on SNP analysis of strains from different wards.

Strengths

• Includes detailed genomic data for 62 bacterial isolates, with specific counts for species, sequence types, and resistance genes.
• Links microbiological data to clinical outcomes, with a specific finding that 83.3% of deceased patients were admitted to the ICU.
• Covers a ten-year time span (2016-2025), providing a longitudinal view of infection trends.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single tertiary hospital, which may limit generalizability to other settings.

Provenance

Source

figshare, author Shenyun Cao.

Collection Method

Retrospective analysis of 62 non-duplicate CRE strains using VITEK-2 Compact for MICs and Illumina NovaSeq for whole-genome sequencing.

Time Range

2016 to 2025

Freshness

Last updated 2026-06-02 05:42:28; freshness should be verified.