CCR1+ Monocyte Data for Bronchopulmonary Dysplasia Research

A 2026 study by Yingjuan Geng investigates myeloid cell roles in bronchopulmonary dysplasia (BPD). The dataset likely contains single-cell transcriptomic data from mouse lung and flow cytometry data from human blood, focusing on CCR1+ monocytes and downstream factors S100A8 and MMP8. It is shared under a CC-BY-4.0 license.

Use Cases

• Identify myeloid cell subpopulations associated with BPD based on single-cell transcriptomic data mentioned in the description
• Validate human BPD blood markers based on flow cytometry analysis of CCR1+ monocytes
• Investigate molecular pathways regulating S100A8 and MMP8 production based on findings in isolated monocytes
• Explore potential clinical biomarkers for BPD based on the study's focus on S100A8 and MMP8

Strengths

• Data integrates findings from both mouse models and human blood samples, as described.
• The study systematically investigates multiple myeloid subpopulations, including CCR1+ monocytes, CD74+ macrophages, and CD63+ neutrophils.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (19.4 KB), suggesting limited scope or summary-level data.

Provenance

Source

figshare

Collection Method

Likely contains experimental data from single-cell RNA sequencing, flow cytometry, and immunofluorescence staining as described.

Freshness

Last updated 2026-05-01 04:16:21; freshness should be verified.