Review of Ceramides as Biomarkers for Major Depressive Disorder and Suicide Risk

A narrative review authored by Martin G. Garcia-Juarez, last updated in April 2026, examining the role of ceramides and lipid metabolism as potential biomarkers in major depressive disorder, treatment-resistant depression, and suicidal vulnerability. The 16.3 KB document synthesizes evidence from lipidomic, neuroinflammatory, and translational studies to propose an immunometabolic framework for these conditions.

Use Cases

• Literature synthesis on ceramide species (e.g., C16–C24:1) and their correlation with depression severity
• Hypothesis generation for immunometabolic drivers of treatment-resistant depression based on integrated pathways
• Informing study design for longitudinal, multi-omic biomarker research in precision psychiatry

Strengths

• Licensed under CC-BY-4.0 for open reuse.
• Author and last update date (2026-04 14) are explicitly provided.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is a 16.3 KB document, indicating a limited scope of primary data.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Martin G. Garcia-Juarez.

Collection Method

Narrative review synthesizing existing literature.

Time Range

Review covers studies up to its publication date.

Freshness

Last updated 2026-04-14 05:39:00.

Geography

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