Streptomyces sp. NELs-40: Genomic and Antibacterial Efficacy Data

Mamy Jayne Nelly Rajaofera published this dataset on figshare in 2026. It contains genomic characterization and antibacterial efficacy results for Streptomyces sp. strain NELs-40 against methicillin-resistant Staphylococcus aureus (MRSA). The data includes a complete genome sequence of 7,973,786 bp, 49 biosynthetic gene clusters, and results from antibacterial assays including inhibition zones and MIC values.

Use Cases

• Training models to predict antimicrobial activity based on genomic features like biosynthetic gene clusters.
• Analyzing the relationship between fermentation optimization parameters (e.g., pH) and antimicrobial compound yield.
• Benchmarking new Streptomyces strains against the genomic and efficacy profile of NELs-40.
• Identifying potential novel antimicrobial metabolites from the 23 compounds identified via GC–MS analysis.

Strengths

• Includes a complete, high-quality genome assembly of 7,973,786 bp with 71.76% GC content.
• Provides specific, quantitative antibacterial results, including a 37 mm inhibition zone and an MIC of 125 μg/mL against MRSA ATCC 43300.
• Contains detailed taxonomic classification data, including ANI, AAI, and dDDH values against two reference genomes.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (17.0 KB), suggesting it is a summary table rather than raw experimental data.

Provenance

Source

Mamy Jayne Nelly Rajaofera via figshare.

Collection Method

Data was generated through genomic sequencing (Illumina HiSeq X10), bioinformatic analysis (antiSMASH, CompareM, TYGS), and laboratory assays (well diffusion, MIC, GC–MS).

Freshness

Last updated 2026-05-29 06:07:46; freshness should be verified.