Klebsiella Aerogenes Strain S_KLB Characterization from a Ground Thrush

A Klebsiella aerogenes bacterial strain, designated S_KLB, was isolated from the lung of a deceased ground thrush. The dataset describes its cultural characteristics, multidrug resistance profile, virulence gene repertoire, and pathogenic mechanisms in a murine pneumonia model. Author Mingao Sun uploaded the study document to figshare under a CC-BY-4.0 license on May 12, 2026.

Use Cases

• Study antibiotic resistance patterns based on the described resistance to imipenem and oxacillin.
• Analyze virulence gene profiles based on the described presence of siderophores, fimbriae, efflux pumps, and metabolic factors.
• Investigate host-pathogen interactions based on the described murine pneumonia model and associated inflammatory cytokine upregulation.
• Examine bacterial signaling pathway activation based on the described NF-κB, STAT3, and p38 MAPK pathway data.

Strengths

• The description provides specific details on the strain's resistance to a majority of tested antibiotics, including imipenem and oxacillin.
• The dataset includes results from multiple experimental methods: PCR, qPCR, Western blotting, and histopathological staining.
• The study elucidates a specific pathogenic mechanism involving the activation of NF-κB, STAT3, and p38 MAPK signaling cascades.

Limitations

• The dataset is a 19.1 KB DOCX file, suggesting limited raw data and a primary focus on textual results and discussion.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

Mingao Sun

Collection Method

The strain was isolated from a deceased ground thrush and characterized through laboratory assays and an animal infection model.

Freshness

Last updated 2026-05-12 05:43:32; freshness should be verified.