Endometrial Renin-Angiotensin System Gene Expression Across Cycle Phases

30 endometrial tissue samples from proliferative, mid-secretory, and late-secretory phases quantify mRNA and protein levels of prorenin, prorenin receptor, and angiotensinogen. Tess L. Symington authored this study, which was last updated on 2026-04-28. Findings suggest the renin–angiotensin system may regulate stromal regeneration and proliferation.

Use Cases

• Analyze mRNA expression differences across menstrual cycle phases based on qPCR data for REN, ATP6AP2, and AGT
• Study spatial protein localization patterns in endometrial tissue based on immunohistochemistry and HALO image analysis
• Investigate potential regulatory roles of the renin–angiotensin system in endometrial stromal regeneration

Strengths

• Includes 10 samples per menstrual cycle phase (proliferative, mid-secretory, late-secretory)
• Quantifies both mRNA expression via qPCR and protein localization via immunohistochemistry
• Analyzes data with mixed effects analysis to account for cell type and phase interactions

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Dataset size is 16.2 KB, indicating a very limited scope

Provenance

Source

figshare

Collection Method

Endometrial tissue collection and analysis via qPCR and immunohistochemistry.

Freshness

Last updated 2026-04-28 04:29:12; freshness should be verified