CHG Index and Incident Impaired Fasting Glucose in a Chinese Adult Cohort

Duo Yang's retrospective longitudinal cohort study analyzes the association between the Cholesterol, HDL, and Glucose (CHG) index and incident impaired fasting glucose (IFG). The dataset includes data from 100,802 Chinese adults with normal baseline fasting plasma glucose, with 12,414 participants developing IFG during follow-up. The study was published on figshare in 2026 under a CC-BY-4.0 license.

Use Cases

• Validate the CHG index as a predictor for incident impaired fasting glucose based on the described longitudinal analysis.
• Investigate nonlinear threshold effects in biomarker-disease relationships based on the reported inflection point at a CHG index of 5.259.
• Conduct subgroup analyses on diabetes risk factors across different populations as referenced in the study methodology.
• Develop early screening tools for prediabetes using routine lipid and glucose test results as suggested by the composite CHG index.

Strengths

• Dataset is derived from a large cohort of 100,802 Chinese adults.
• Longitudinal design tracks incident impaired fasting glucose, with 12,414 cases identified.
• Analysis includes multivariable adjustment for demographic, anthropometric, clinical, and lifestyle factors.
• Study explores a novel composite biomarker (CHG index) calculated from routine clinical tests.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying analytical dataset is unknown, which may limit suitability assessment.
• Data may reflect geographic and selection bias inherent to the specific health screening cohort source.

Provenance

Source

Duo Yang via figshare.

Collection Method

Retrospective longitudinal cohort study using data from a publicly available health screening cohort.

Freshness

Last updated 2026-06-02 14:01:30; freshness should be verified.

Geography

China