Meta-Analysis Data on Circulating Tumor DNA and Survival in Gastric Cancer Surgery

Twenty-five studies comprising 60 datasets were synthesized in this meta-analysis. The data, compiled by Jidong Bian and last updated in May 2026, quantifies the association between ctDNA positivity and survival outcomes in patients with resectable gastric cancer. It includes pooled hazard ratios for overall and disease-free survival from studies up to May 2025.

Use Cases

• Assess the prognostic value of ctDNA for overall survival based on pooled hazard ratios
• Compare the strength of pre-operative versus post-operative ctDNA measurements for predicting disease-free survival
• Evaluate evidence sufficiency for clinical relevance using trial sequential analysis results
• Conduct subgroup analyses based on detection platforms, sample sources, and patient regions mentioned in the description

Strengths

• Methodologically rigorous synthesis focusing exclusively on resectable gastric cancer
• Includes trial sequential analysis to evaluate evidence sufficiency
• Pooled results from 25 studies (60 datasets) with specific hazard ratios and confidence intervals

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of studies from four major databases up to May 2025.

Time Range

Studies up to May 2025

Freshness

Last updated 2026-05-18 05:41:21