Embryo Development Patterns and Live Birth Outcomes from 3,103 Blastocyst Transfers

A retrospective time-lapse study of 3,103 transferred autologous blastocysts, authored by Emma Adolfsson and last updated in April 2026. It evaluates how early cleavage patterns, morula compaction behavior, and blastocyst quality influence clinical pregnancy and live birth rates. The analysis includes unadjusted and multivariable models adjusting for maternal age and blastocyst developmental day.

Use Cases

• Predicting live birth likelihood based on blastocyst morphology categories (top, good, low).
• Analyzing the association between early cleavage patterns (normal/abnormal) and pregnancy rates.
• Modeling the impact of morula compaction behavior (full/partial) on clinical outcomes.
• Investigating the independent predictive power of blastocyst developmental day versus maternal age.

Strengths

• Includes 3,103 transferred blastocysts, providing a substantial clinical cohort.
• Reports specific outcome rates, such as a 38.9% live birth rate for top-quality blastocysts from normal, fully compacted embryos.
• Employs multivariable analysis adjusting for key confounders like maternal age and blastocyst age.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

Emma Adolfsson, via figshare.

Collection Method

Retrospective time-lapse study.

Time Range

The study period is not specified in the provided input.

Freshness

Last updated 2026-04-15 05:22:52; freshness should be verified.

Geography

The geographic coverage is not specified in the provided input.