Chronic Thromboembolic Pulmonary Hypertension Patient Outcomes in Kazakhstan

110 adult patients diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) in Kazakhstan between 2018 and 2024. The dataset compares clinical characteristics and survival outcomes between patients who underwent pulmonary endarterectomy and those receiving medical therapy alone, with a median follow-up of 39 months. It was collected by Anara Abbay from the sole national CTEPH referral center.

Use Cases

• Compare baseline hemodynamic parameters between surgical and medical therapy groups to identify selection criteria.
• Analyze the median delay from symptom onset to referral of 24 months to study diagnostic pathways.
• Assess improvements in pulmonary hemodynamics and right-heart function pre- and post-pulmonary endarterectomy in the surgical subgroup.
• Evaluate long-term survival over a median follow-up of 39 months across treatment groups.
• Track the annual number of PEA procedures over time to measure treatment access trends.

Strengths

• Contains data on 110 consecutively diagnosed patients from a national referral center.
• Includes a median follow-up period of 39 months for survival analysis.
• Covers a specific time range from 2018 to 2024, providing recent clinical insights.
• Focuses on a geographically underrepresented region (Central Asia/Kazakhstan) for this condition.

Limitations

• Small sample size of 110 patients limits statistical power for subgroup analyses.
• Retrospective study design may introduce selection or information bias.
• The survival difference between groups did not reach statistical significance.
• Data is contained in a DOCX report, requiring extraction for computational analysis.

Provenance

Source

Sole national CTEPH referral center in Kazakhstan.

Collection Method

Retrospective analysis of consecutive adult patients diagnosed between 2018 and 2024.

Time Range

2018 to 2024

Freshness

Data current through 2024, with the record last updated in March 2026.

Geography

Kazakhstan, Central Asia