Table 1_Clinical efficacy of different blood purification modes on severe acute pancreatit

A systematic review and network meta-analysis of 45 randomized controlled trials involving 3,707 patients, evaluating different blood purification modes for Severe Acute Pancreatitis. The analysis, conducted by Peihong Li and published on figshare in 2026, used data from English and Chinese databases up to December 2025. It ranks interventions by efficacy on outcomes like APACHE II scores, amylase levels, and inflammatory markers.

Use Cases

• Ranking blood purification interventions based on Surface Under the Cumulative Ranking Curve (SUCRA) values for clinical efficacy.
• Comparing the impact of different modes (e.g., hemoperfusion + continuous renal replacement therapy) on Acute Physiology and Chronic Health Evaluation (APACHE II) scores.
• Analyzing the effect of combined therapies on secondary outcomes like amylase (AMS), C-reactive protein (CRP), and interleukin-6 (IL-6) levels.
• Evaluating the relationship between blood purification and mortality outcomes in Severe Acute Pancreatitis patients.

Strengths

• Includes 45 randomized controlled trials, a substantial evidence base for meta-analysis.
• Covers 3,707 patient records, providing a meaningful sample size for statistical power.
• Assesses multiple clinical outcomes including APACHE II scores, amylase, CRP, IL-6, triglycerides, and renal function.
• Uses established quality assessment (RoB 2.0) and statistical methods (STATA 18.0, random-effects model).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying analysis data is unknown, which may limit suitability assessment.
• The description notes loop inconsistency and unresolved heterogeneity for certain outcomes, warranting cautious interpretation.

Provenance

Source

Peihong Li via figshare.

Collection Method

Systematic review and network meta-analysis of clinical trials from databases including PubMed, Embase, Cochrane Library, Web of Science, CNKI, VIP, Wangfang Data, and CBM.

Time Range

Trials published through December 1, 2025.

Freshness

Last updated 2026-05-29 05:31:42; freshness should be verified.