ST3672 NDM-1-Producing Vibrio parahaemolyticus: Clinical and Genomic Characterization

A novel, multidrug-resistant Vibrio parahaemolyticus strain (VP1434) was isolated from a patient in a food poisoning outbreak. The study by Chengpei Ni, published in 2026, includes whole-genome sequencing data, antimicrobial susceptibility profiles against 29 antibiotics, and mouse infection results. It represents the first report of a blaNDM-1-positive clinical V. parahaemolyticus isolate, highlighting a plasmid-mediated resistance threat.

Use Cases

• Phylogenetic analysis of Vibrio parahaemolyticus based on the whole-genome sequencing data mentioned.
• Studying plasmid-mediated multidrug resistance transfer based on the conjugation experiments described.
• Investigating virulence factors in foodborne pathogens based on the identification of 185 VFs, including tlh and trh.
• Assessing pathogenicity of clinical isolates based on the mouse infection experiment results comparing lethality.

Strengths

• Includes whole-genome sequencing data for a novel sequence type (ST3672).
• Provides antimicrobial susceptibility test results against 29 distinct antibiotics.
• Contains experimental validation of plasmid transferability and mouse infection pathogenicity.
• Identifies 185 virulence factors within the characterized strain.

Limitations

• The dataset is very small (20.1 KB), suggesting it is likely a summary document rather than raw sequence or phenotypic data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.

Provenance

Source

figshare, authored by Chengpei Ni.

Collection Method

Clinical isolate characterization via antimicrobial testing, whole-genome sequencing, plasmid analysis, and mouse infection experiments.

Freshness

Last updated 2026-04-22 05:48:31; freshness should be verified.