Clinical Outcomes of Preimplantation Genetic Testing for Chromosomal Inversions, 2019-2024

A retrospective analysis of preimplantation genetic testing outcomes for couples with chromosomal inversions, conducted between January 2019 and December 2024. The study compares euploid and aneuploid blastocyst rates across different genetic subgroups, including PGT-INV, PGT-PV, PGT-A, and PGT-SR. The dataset was authored by Yutong Li and shared under a CC-BY-4.0 license.

Use Cases

• Compare euploid blastocyst rates between couples with chromosomal inversions and those with normal karyotypes or polymorphic variations, as described in the study.
• Analyze the influence of carrier gender (female vs. male inversion) on aneuploidy rates, a key finding mentioned in the description.
• Investigate the relationship between inverted fragment size and the proportion of aneuploid blastocysts, which the description indicates exhibits a linear trend.
• Evaluate differences in aneuploidy rates between pericentric and paracentric inversions, a statistically significant result reported in the description.

Strengths

• Includes specific statistical results, such as a 38.94% aneuploid blastocyst rate for pericentric inversions versus 23.60% for paracentric inversions.
• Covers a defined time range from January 2019 to December 2024.
• Data is shared under a permissive CC-BY-4.0 license, facilitating reuse.

Limitations

• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (21.6 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Retrospective clinical study.

Time Range

January 2019 to December 2024

Freshness

Last updated 2026-04-24 09:13:36; freshness should be verified.